Fibroblast apoptosis and caspase-8 activation in aseptic loosening
نویسندگان
چکیده
منابع مشابه
Fenretinide-Induced Caspase-8 Activation and Apoptosis in Metastatic Neuroblasts
1. Centre National de Recherche Scientifique, Unité Mixte de Recherche 8126, Institut Fédératif de Recherche 54, Institut Gustave Roussy, Villejuif, France. 2. University Hospital CHUV, Pediatric Oncology Research, Department of Pediatrics, Lausanne, Switzerland. § Current address: Lawrence Berkeley National Lab, 1 Cyclotron Rd., MS-977-225A, University of California, Berkeley, CA 94720, USA 3....
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Recently, caspase-2 was shown to act upstream of mitochondria in stress-induced apoptosis. Activation of caspase-8, a key event in death receptor-mediated apoptosis, also has been demonstrated in death receptor-independent apoptosis. The regulation of these initiator caspases, which trigger the mitochondrial apoptotic pathway, is unclear. Here we report a potential regulatory role of caspase-2 ...
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OBJECTIVE Resveratrol is a naturally occurring polyphenol, which possesses chemotherapeutic potential through its ability to trigger apoptosis. The objective of this study was to investigate the major determinant for the apoptotic cell death induction by resveratrol in fibroblast-like synoviocytes (FLS) derived from patients with RA. METHODS The effect of resveratrol on apoptotic cell death w...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2003
ISSN: 0142-9612
DOI: 10.1016/s0142-9612(03)00276-x